Hydrochloric Acid → HCID 13355662, compound

HRID 1111960Notes

Reaction equation

Cl.[NH2:2][C:3]1[C:8]([C:9]#[N:10])=[CH:7][C:6]([C:11](=[O:17])[CH2:12][NH:13][CH:14]([CH3:16])[CH3:15])=[CH:5][C:4]=1[Br:18].[BH4-].[Na+]>>[NH2:2][C:3]1[C:8]([C:9]#[N:10])=[CH:7][C:6]([CH:11]([OH:17])[CH2:12][NH:13][CH:14]([CH3:15])[CH3:16])=[CH:5][C:4]=1[Br:18]

Participants

Reactant 3

HCID 313Hydrochloric Acid

HCID 4311764Sodium borohydride

HCID 13355653HCID 13355653, compound

Product 1

HCID 13355662HCID 13355662, compound

Procedure

m.p. of the hydrochloride: 186°-189° C., was prepared from 4'-amino-3'-bromo-5'-cyano-2-isopropylamino-acetophenone and sodium borohydride analogous to Example 2.

Sources & evidence

ORD record: ord-bba3b7178a784a90becb2de70784d783
Source dataset: uspto-grants-1978_10
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US04119710

Reaction notes

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