Hydrochloric Acid → HCID 13355577, compound

HRID 1111972Notes

Reaction equation

HRID 1111972 reaction equation
Cl.[NH2:2][C:3]1[C:8]([I:9])=[CH:7][C:6]([C:10](=[O:17])[CH2:11][NH:12][CH:13]2[CH2:16][CH2:15][CH2:14]2)=[CH:5][C:4]=1[F:18]>>[NH2:2][C:3]1[C:8]([I:9])=[CH:7][C:6]([CH:10]([OH:17])[CH2:11][NH:12][CH:13]2[CH2:16][CH2:15][CH2:14]2)=[CH:5][C:4]=1[F:18]

Participants

3

Reactant 2

HCID 313Hydrochloric AcidHCID 13355572HCID 13355572, compound

Product 1

HCID 13355577HCID 13355577, compound

Procedure

m.p. of the hydrochloride: 197°-199° C. (decomp.), was prepared from 4'-amino-2-cyclobutylamino-3'-fluoro-5'-iodo-acetophenone analogous to Example 49.

Sources & evidence

ORD record
ord-93c2b64a515a4018bfaea62a3768f09b
Source dataset
uspto-grants-1978_10
Patent number
US04119710

Reaction notes

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