Hydrochloric Acid → HCID 41846, compound
Reaction equation
Cl.[NH2:2][C:3]1[C:8]([I:9])=[CH:7][C:6]([C:10](=[O:17])[CH2:11][NH:12][C:13]([CH3:16])([CH3:15])[CH3:14])=[CH:5][C:4]=1[F:18]>>[NH2:2][C:3]1[C:8]([I:9])=[CH:7][C:6]([CH:10]([OH:17])[CH2:11][NH:12][C:13]([CH3:14])([CH3:16])[CH3:15])=[CH:5][C:4]=1[F:18]Participants
3
Procedure
m.p. of the hydrochloride: 207°-209° C. (decomp.), was prepared from 4'-amino-2-tert.butylamino-3'-fluoro-5'-iodo-acetophenone analogous to Example 49.
Sources & evidence
- ORD record
- ord-c1523468889341fcba182a0f778afdbd
- Source dataset
- uspto-grants-1978_10
- Patent number
- US04119710
Reaction notes
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