Hydrochloric Acid → HCID 3062318, compound
Reaction equation
Cl.[NH2:2][C:3]1[C:8]([F:9])=[CH:7][C:6]([C:10](=[O:16])[CH2:11][NH:12][CH:13]([CH3:15])[CH3:14])=[CH:5][C:4]=1[C:17]#[N:18]>>[NH2:2][C:3]1[C:8]([F:9])=[CH:7][C:6]([CH:10]([OH:16])[CH2:11][NH:12][CH:13]([CH3:15])[CH3:14])=[CH:5][C:4]=1[C:17]#[N:18]Participants
3
Procedure
m.p. of the hydrochloride: 182°-184° C. (decomp.), was prepared from 4'-amino-3'-cyano-5'-fluoro-2-isopropylaminoacetophenone analogous to Example 49.
Sources & evidence
- ORD record
- ord-e9d830ef83e94700805eef3ea72c2e91
- Source dataset
- uspto-grants-1978_10
- Patent number
- US04119710
Reaction notes
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