Hydrochloric Acid → HCID 41848, compound
Reaction equation
Cl.[NH2:2][C:3]1[C:8]([F:9])=[CH:7][C:6]([C:10](=[O:17])[CH2:11][NH:12][C:13]([CH3:16])([CH3:15])[CH3:14])=[CH:5][C:4]=1[C:18]#[N:19]>>[NH2:2][C:3]1[C:8]([F:9])=[CH:7][C:6]([CH:10]([OH:17])[CH2:11][NH:12][C:13]([CH3:16])([CH3:14])[CH3:15])=[CH:5][C:4]=1[C:18]#[N:19]Participants
3
Procedure
m.p. of the hydrochloride: 242°-243° C. (decomp.), was prepared from 4'-amino-2-tert.butylamino-3'-cyano-5'-fluoroacetophenone analogous to Example 49.
Sources & evidence
- ORD record
- ord-99c0d2b139094c2d9fb644e05957217c
- Source dataset
- uspto-grants-1978_10
- Patent number
- US04119710
Reaction notes
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