Hydrochloric Acid → HCID 13355593, compound

HRID 1111979Notes

Reaction equation

Cl.[NH2:2][C:3]1[C:8]([F:9])=[CH:7][C:6]([C:10](=[O:18])[CH2:11][NH:12][C:13]([CH2:16][CH3:17])([CH3:15])[CH3:14])=[CH:5][C:4]=1[C:19]#[N:20]>>[NH2:2][C:3]1[C:8]([F:9])=[CH:7][C:6]([CH:10]([OH:18])[CH2:11][NH:12][C:13]([CH2:16][CH3:17])([CH3:14])[CH3:15])=[CH:5][C:4]=1[C:19]#[N:20]

Participants

Reactant 2

HCID 313Hydrochloric Acid

HCID 13355585HCID 13355585, compound

Product 1

HCID 13355593HCID 13355593, compound

Procedure

m.p. of the hydrochloride: 172°-175° C. (decomp.)., was prepared from 4'-amino-3'-cyano-5'-fluoro-2-tert.pentylaminoacetophenone analogous to Example 49.

Sources & evidence

ORD record: ord-b650e28840f34af0989a039ed766b141
Source dataset: uspto-grants-1978_10
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US04119710

Reaction notes

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