Hydrochloric Acid → HCID 13355760, compound
Reaction equation
Cl.[NH2:2][C:3]1[C:8]([C:9]([F:12])([F:11])[F:10])=[CH:7][C:6]([CH:13]([OH:21])[CH2:14][NH:15][CH:16]2[CH2:20][CH2:19][CH2:18][CH2:17]2)=[CH:5][C:4]=1Br>>[NH2:2][C:3]1[CH:4]=[CH:5][C:6]([CH:13]([OH:21])[CH2:14][NH:15][CH:16]2[CH2:20][CH2:19][CH2:18][CH2:17]2)=[CH:7][C:8]=1[C:9]([F:10])([F:11])[F:12]Participants
3
Procedure
m.p. of the hydrochloride: 144°-145° C., was prepared from 1-(4'-amino-3'-bromo-5'-trifluoromethyl-phenyl)-2-cyclopentylamino-ethanol analogous to Example 51.
Sources & evidence
- ORD record
- ord-7a3f5a36de9042e3b393392d4e02dc98
- Source dataset
- uspto-grants-1978_10
- Patent number
- US04119710
Reaction notes
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