Hydrogen Bromide → HCID 13355754, compound

HRID 1111981Notes

Reaction equation

Br.[NH2:2][C:3]1[C:8]([C:9]#[N:10])=[CH:7][C:6]([CH:11]([OH:18])[CH2:12][NH:13][CH:14]2[CH2:17][CH2:16][CH2:15]2)=[CH:5][C:4]=1Br>>[NH2:2][C:3]1[CH:4]=[CH:5][C:6]([CH:11]([OH:18])[CH2:12][NH:13][CH:14]2[CH2:17][CH2:16][CH2:15]2)=[CH:7][C:8]=1[C:9]#[N:10]

Participants

Reactant 2

HCID 260Hydrogen Bromide

HCID 13355664HCID 13355664, compound

Product 1

HCID 13355754HCID 13355754, compound

Procedure

m.p. of the hydrobromide: >193° C. (decomp.), was prepared from 1-(4'-amino-3'-bromo-5'-cyano-phenyl)-2-cyclobutylamino-ethanol analogous to Example 51.

Sources & evidence

ORD record: ord-2964e13611dd46f3a835d3a244df58c5
Source dataset: uspto-grants-1978_10
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US04119710

Reaction notes

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