Hydrochloric Acid → HCID 22765827, compound
Reaction equation
Cl.[NH2:2][C:3]1[C:8]([C:9]#[N:10])=[CH:7][C:6]([C:11](=[O:19])[CH2:12][N:13]([OH:18])[C:14]([CH3:17])([CH3:16])[CH3:15])=[CH:5][C:4]=1[Cl:20]>>[NH2:2][C:3]1[C:8]([C:9]#[N:10])=[CH:7][C:6]([CH:11]([OH:19])[CH2:12][N:13]([OH:18])[C:14]([CH3:17])([CH3:15])[CH3:16])=[CH:5][C:4]=1[Cl:20]Participants
3
Procedure
m.p. of the hydrochloride: 228°-230° C. (decomp.), was prepared from 4'-amino-3'-chloro-5'-cyano-2-(hydroxy-tert.butylamino)-acetophenone analogous to Example 48.
Sources & evidence
- ORD record
- ord-7f22cde8a04b43ee87ec82779064e3b1
- Source dataset
- uspto-grants-1978_10
- Patent number
- US04119710
Reaction notes
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