Hydrochloric Acid → HCID 22765853, compound

HRID 1111990Notes

Reaction equation

HRID 1111990 reaction equation
Cl.[NH2:2][C:3]1[C:8]([C:9]#[N:10])=[CH:7][C:6]([C:11](=[O:19])[CH2:12][N:13]([OH:18])[C:14]([CH3:17])([CH3:16])[CH3:15])=[CH:5][C:4]=1[Br:20]>>[NH2:2][C:3]1[C:8]([C:9]#[N:10])=[CH:7][C:6]([CH:11]([OH:19])[CH2:12][N:13]([OH:18])[C:14]([CH3:17])([CH3:15])[CH3:16])=[CH:5][C:4]=1[Br:20]

Participants

3

Reactant 2

HCID 313Hydrochloric AcidHCID 22765821HCID 22765821, compound

Product 1

HCID 22765853HCID 22765853, compound

Procedure

m.p. of the hydrochloride: 221°-222° C., was prepared from 4'-amino-3'-bromo-5'-cyano-2-(hydroxy-tert.butylamino)-acetophenone analogous to Example 48.

Sources & evidence

ORD record
ord-8ccf4ecdfd494eed904f3759e25fcc39
Source dataset
uspto-grants-1978_10
Patent number
US04119710

Reaction notes

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