HuagongsheHuagongshe Chemistry Print Report · For research reference only
Methylamine → HCID 178484998, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Methylamine | HCID 6329 | — |
| Reactant | 1-Cyano-2-methyl-3-(2-(((5-methyl-1H-imidazol-4-yl)methyl)thio)ethyl)isothiourea | HCID 103630 | — |
| Solvent | Ethanol | HCID 702 | — |
| Product | HCID 178484998 | HCID 178484998 | — |
Reaction Steps
A solution of 75 ml. of 33% methylamine in ethanol was added to a solution of 10.1 g. of N-cyano-N'-[2-(5-methyl-4-imidazolylmethylthio)ethyl]-S-methylisothiourea in 30 ml. of ethanol. The reaction mixture was set aside at ambient temperature for 2.5 hours. Following concentration under reduced pressure, the residue was recrystallized twice from isopropanolpetroleum ether to give N-cyano-N'-methyl-N"-[2-(5-methyl-4-imidazolylmethylthio)ethyl]guanidine, m.p. 141°-143°.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04119781 |
| Source dataset | uspto-grants-1978_10 |
| ORD ID | ord-9d382f4be95141e4ba1456d193e8f8c0 |
| Source note | uspto-grants-1978_10 |