Triethylamine → 2-(5-Methyl-4-imidazolylmethylthio)ethyl N-[2-(5-methyl-4-imidazolylmethylthio)ethyl]dithiocarbamate
Reaction equation
Cl.[CH3:2][C:3]1[NH:7][CH:6]=[N:5][C:4]=1[CH2:8][S:9][CH2:10][CH2:11][N:12]=[C:13]=[S:14].C(N(CC)CC)C.[CH3:22][C:23]1[NH:27][CH:26]=[N:25][C:24]=1[CH2:28][S:29][CH2:30][CH2:31][SH:32]>>[CH3:2][C:3]1[NH:7][CH:6]=[N:5][C:4]=1[CH2:8][S:9][CH2:10][CH2:11][NH:12][C:13](=[S:14])[S:32][CH2:31][CH2:30][S:29][CH2:28][C:24]1[N:25]=[CH:26][NH:27][C:23]=1[CH3:22]Participants
4
Procedure
5-Methyl-4-(2-isothiocyanatoethylthiomethyl)imidazole hydrochloride may be treated with one equivalent of triethylamine and 2-(5-methyl-4-imidazolylmethylthio)ethanethiol according to the general procedure of Example 1(b) to give the title product.
Sources & evidence
- ORD record
- ord-271a40e5037c46a085dc0572a1566179
- Source dataset
- uspto-grants-1978_10
- Patent number
- US04120972
Reaction notes
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