Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Triethylamine | HCID 8471 | — |
| Reactant | Methyl L-phenylalaninate hydrochloride | HCID 75736 | — |
| Reactant | L-Phenylalanine, N-[(1,1-dimethylethoxy)carbonyl]- | HCID 77857 | — |
| Solvent | Tetrahydrofuran | HCID 8028 | — |
| Product | HCID 131711306 | HCID 131711306 | — |
Reaction Steps
788 mg of triethylamine are added to a mixture of 648 mg of Phe-OMe.HCl and 1.641 g of Boc-Phe≈SO2 in 20 ml of absolute tetrahydrofuran, whereupon the mixture becomes deep red. It is stirred for 1 hour at 20° C. The pale yellow mixture is then worked up as described in Example D 1.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| Patent number | US04122090 |
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| Source dataset | uspto-grants-1978_10 |
|---|
| ORD ID | ord-00690b1ecae944af8ebeb023e864d2b5 |
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| Source note | uspto-grants-1978_10 |
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