Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Triethylamine | HCID 8471 | — |
| Reactant | L-Phenylalanine, N-[(1,1-dimethylethoxy)carbonyl]- | HCID 77857 | — |
| Reactant | HCID 131711311 | HCID 131711311 | — |
| Solvent | Tetrahydrofuran | HCID 8028 | — |
| Product | HCID 131711310 | HCID 131711310 | — |
Reaction Steps
420 mg of triethylamine are added to a mixture of 891 mg of Pro-Pro-Phe-Phe-OMe.HCl D 14 and 875 mg of Boc-Phe≈SO2 in 20 ml of absolute tetrahydrofuran, whereupon the mixture develops a deep red coloration. It is stirred for 2 hours at 20° C. The pale yellow mixture is then worked up as described in Example D 1.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| Patent number | US04122090 |
|---|
| Source dataset | uspto-grants-1978_10 |
|---|
| ORD ID | ord-26313fc4190c436bb110c7f87ac1beeb |
|---|
| Source note | uspto-grants-1978_10 |
|---|
