HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
UP 614-04 → 2-(1-Phenyl-2,3-dihydro-imidazo-(4,5-b)pyridin-2-on-3-yl-methyl)-morpholine maleate
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|---|---|---|
| Edukt | UP 614-04 | HCID 134375 | — |
| Edukt | Maleic Acid | HCID 444266 | — |
| Edukt | 4-Benzyl-2-(1-phenyl-2,3-dihydro-imidazo(4,5-b)pyridin-2-on-3-yl-methyl)-morpholine hydrochloride | HCID 70601730 | — |
| Lösungsmittel | Isopropanol | HCID 3776 | — |
| Produkt | 2-(1-Phenyl-2,3-dihydro-imidazo-(4,5-b)pyridin-2-on-3-yl-methyl)-morpholine maleate | HCID 86736079 | — |
Reaktionsschritte
19 g of 4-benzyl-2-(1-phenyl-2,3-dihydro-imidazo-(4,5-b)pyridin-2-on-3yl-methyl)-morpholine hydrochloride are treated in accordance with part (a) of Example 2. The oil obtained is dissolved in hot isopropanol. A hot solution of maleic acid in isopropanol is added. The salt precipitates slowly. Recrystallization from isopropanol gives 5 g of 2-(1-phenyl-2,3-dihydro-imidazo-(4,5-b)pyridin-2-on-3-yl-methyl)-morpholine maleate, m.p. 190° C.
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patentnummer | US04122175 |
| Quelldatensatz | uspto-grants-1978_10 |
| ORD ID | ord-246bfad5f0804e13a0b57b1bc9653651 |
| Quellennotiz | uspto-grants-1978_10 |