HuagongsheHuagongshe Chemistry Print Report · For research reference only
Clofibric Acid → Apovincamine clofibrate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Clofibric Acid | HCID 2797 | — |
| Reactant | Apovincamine | HCID 71204 | — |
| Product | Apovincamine clofibrate | HCID 70622092 | 121% |
Reaction Steps
The preceding example is repeated starting from 3.36 g of apovincamine and 2.14 g of clofibric acid. The final product (3.5 g) is a low melting solid, m.p. 65° C., which is insoluble in water and soluble in alcohol, with an apovincamine content of 61%.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04122179 |
| Source dataset | uspto-grants-1978_10 |
| ORD ID | ord-ef774ae28b334877bd8c60360e247aac |
| Source note | uspto-grants-1978_10 |