Tetrahydrofuran → 1-(t-Butoxycarbonyl)-4-(2-tributylstannylethyn-1-yl)piperidine

HRID 111239Notes

Reaction equation

HRID 111239 reaction equation
[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6](=[O:7])[N:8]1[CH2:9][CH2:10][CH:11]([CH:14]=[C:15]([Br:16])[Br:17])[CH2:12][CH2:13]1.[CH2:18]([Li:19])[CH2:20][CH2:21][CH3:22].[CH2:23]([CH2:24][CH2:25][CH3:26])[Sn:27]([CH2:28][CH2:29][CH2:30][CH3:31])([CH2:32][CH2:33][CH2:34][CH3:35])[Cl:36].[CH2:37]1[O:38][CH2:39][CH2:40][CH2:41]1>>[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6](=[O:7])[N:8]1[CH2:9][CH2:10][CH:11]([C:14]#[C:15][Sn:27]([CH2:23][CH2:24][CH2:25][CH3:26])([CH2:28][CH2:29][CH2:30][CH3:31])[CH2:32][CH2:33][CH2:34][CH3:35])[CH2:12][CH2:13]1

Participants

5

Reactant 4

HCID 8028TetrahydrofuranHCID 15096Tributyltin ChlorideHCID 11474132Tert-butyl 4-(2,2-dibromovinyl)piperidine-1-carboxylateHCID 178418339Butyllithium

Product 1

HCID 181875621-(t-Butoxycarbonyl)-4-(2-tributylstannylethyn-1-yl)piperidine

Sources & evidence

ORD record
ord-70ed1e0af4cc4490b445e3fc1ee27979
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (2/10)

Reaction notes

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