HuagongsheHuagongshe Chemistry Print Report · For research reference only
Sodium borohydride → N-[[2-[3-(1-Piperidinyl)propoxy]phenyl]methyl]benzeneethanamine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Sodium borohydride | HCID 4311764 | — |
| Reactant | N-[[2-[3-(1-Piperidinyl)propoxy]phenyl]methylene]benzeneethanamine | HCID 21322776 | — |
| Solvent | Methanol | HCID 887 | — |
| Product | N-[[2-[3-(1-Piperidinyl)propoxy]phenyl]methyl]benzeneethanamine | HCID 21322750 | 80.2% |
Reaction Steps
N-[[2-[3-(1-Piperidinyl)propoxy]phenyl]methylene]benzeneethanamine (61.5g) is reduced with 20g of sodium borohydride in 320ml of methanol following the procedure described in Example 1B to yield 49.6g of product as an oil, boiling point 216°-221° C at 0.3-0.4mm of Hg.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04122255 |
| Source dataset | uspto-grants-1978_10 |
| ORD ID | ord-2850cc6f559c4d1da12e93892a134dc9 |
| Source note | uspto-grants-1978_10 |