HuagongsheHuagongshe Chemistry Print Report · For research reference only
1-Phenylpiperazine → 5-phenyl-2-[(4-phenylpiperazin-1-yl)methyl]-1,3-oxazole
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 1-Phenylpiperazine | HCID 7096 | — |
| Reactant | Sodium Carbonate | HCID 10340 | — |
| Reactant | 2-(chloromethyl)-5-phenyl-1,3-oxazole | HCID 2307654 | — |
| Solvent | Ethanol | HCID 702 | — |
| Product | 5-phenyl-2-[(4-phenylpiperazin-1-yl)methyl]-1,3-oxazole | HCID 8688253 | — |
Reaction Steps
A solution of 2-choromethyl-5-phenyloxazole (3.87 g; 0.02 mole) and N-phenylpiperazine (3.25 g; 0.02 mole) in absolute ethanol (60 ml) was boiled and stirred with finely powdered anhydrous sodium carbonate (5 g) for 6 hours.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04123529 |
| Source dataset | uspto-grants-1978_10 |
| ORD ID | ord-bdc4838df5444f51b73e2c351c2ec3e7 |
| Source note | uspto-grants-1978_10 |