Dimethylformamide → Ethyl 1-(4-fluorophenyl)-4-hydroxy-1,3,8-triazaspiro[4.5]dec-3-ene-8-carboxylate

HRID 1113036Notes

Reaction equation

HRID 1113036 reaction equation
[C:1]([NH2:2])(=[O:3])[C:4]1([NH:15][c:16]2[cH:17][cH:18][c:19]([F:22])[cH:20][cH:21]2)[CH2:5][CH2:6][N:7]([C:10](=[O:11])[O:12][CH2:13][CH3:14])[CH2:8][CH2:9]1.[CH3:23][N:24]([CH3:25])[CH:26]=[O:27]>>[C:1]1(=[O:3])[NH:2][CH2:23][N:15]([c:16]2[cH:17][cH:18][c:19]([F:22])[cH:20][cH:21]2)[C:4]12[CH2:5][CH2:6][N:7]([C:10](=[O:11])[O:12][CH2:13][CH3:14])[CH2:8][CH2:9]2

Participants

3

Reactant 2

HCID 6228DimethylformamideHCID 30189781-(Ethoxycarbonyl)-4-(4-fluoroanilino)piperidine-4-carboximidic acid

Product 1

HCID 12834315Ethyl 1-(4-fluorophenyl)-4-hydroxy-1,3,8-triazaspiro[4.5]dec-3-ene-8-carboxylate

Sources & evidence

ORD record
ord-338a695328f94ed3a5128dc872de5374
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (7/10)

Reaction notes

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