Phosphorus oxychloride → 4-chloro-2-pyridin-4-ylquinazoline

HRID 1113047Notes

Reaction equation

HRID 1113047 reaction equation
[P:18]([Cl:19])([Cl:20])([Cl:21])=[O:22].[n:1]1[cH:2][cH:3][c:4](-[c:7]2[n:8][c:9]3[cH:10][cH:11][cH:12][cH:13][c:14]3[c:15](=[O:17])[nH:16]2)[cH:5][cH:6]1>>[n:1]1[cH:2][cH:3][c:4](-[c:7]2[n:8][c:9]3[cH:10][cH:11][cH:12][cH:13][c:14]3[c:15]([Cl:20])[n:16]2)[cH:5][cH:6]1

Participants

3

Reactant 2

HCID 24813Phosphorus oxychlorideHCID 1354126684-Hydroxy-2-(pyridin-4-yl)quinazoline, 4-(4-Hydroxyquinazolin-2-yl)pyridine

Product 1

HCID 47368494-chloro-2-pyridin-4-ylquinazoline

Sources & evidence

ORD record
ord-22d364c3e57848af87671d8de430cfc2
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (7/10)

Reaction notes

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