Bromide ion → 3-Fluoro-2-(5-methoxy-1-methyl-1H-indol-3-yl)-1H-pyrrolo[2,3-b]pyridine

HRID 1113597Notes

Reaction equation

HRID 1113597 reaction equation
[B-:25]([F:26])([F:27])([F:28])[F:29].[B-:30]([F:31])([F:32])([F:33])[F:34].[Br-:22].[CH3:1][O:2][c:3]1[cH:4][c:5]2[c:6](-[c:13]3[cH:14][c:15]4[c:16]([n:17][cH:18][cH:19][cH:20]4)[nH:21]3)[cH:7][n:8]([CH3:12])[c:9]2[cH:10][cH:11]1.[CH3:23][Mg+:24].[Cl:35][CH2:36][N+:37]12[CH2:38][CH2:39][N+:40]([F:41])([CH2:42][CH2:43]1)[CH2:44][CH2:45]2.[O:46]1[CH2:47][CH2:48][CH2:49][CH2:50]1>>[CH3:1][O:2][c:3]1[cH:4][c:5]2[c:6](-[c:13]3[c:14]([F:26])[c:15]4[c:16]([n:17][cH:18][cH:19][cH:20]4)[nH:21]3)[cH:7][n:8]([CH3:12])[c:9]2[cH:10][cH:11]1

Participants

7

Reactant 6

HCID 259Bromide ionHCID 8028TetrahydrofuranHCID 26255Tetrafluoroborate2×HCID 27249341-(Chloromethyl)-4-fluoro-1,4-diazoniabicyclo(2.2.2)octaneHCID 224772272-(5-methoxy-1-methyl-1H-indol-3-yl)-1H-pyrrolo[2,3-b]pyridineHCID 178477777HCID 178477777, compound

Product 1

HCID 224772553-Fluoro-2-(5-methoxy-1-methyl-1H-indol-3-yl)-1H-pyrrolo[2,3-b]pyridine

Sources & evidence

ORD record
ord-6320efd4139246f7ac635b94bd533b10
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (7/10)

Reaction notes

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