Potassium Cation → 2-[2-Fluoro-4-(methylsulfonyl)phenyl]-5-[({1-[3-(1-methylethyl)-1,2,4-oxadiazol-5-yl]-4-piperidinyl}methyl)oxy]pyrazine

HRID 1113718Notes

Reaction equation

HRID 1113718 reaction equation
[CH3:19][S:20]([O:21][CH2:24][CH:25]1[CH2:26][CH2:27][N:28]([c:31]2[n:32][c:33]([CH:36]([CH3:37])[CH3:38])[n:34][o:35]2)[CH2:29][CH2:30]1)(=[O:22])=[O:23].[F:1][c:2]1[c:3](-[c:12]2[n:13][cH:14][c:15]([OH:18])[n:16][cH:17]2)[cH:4][cH:5][c:6]([S:8](=[O:9])(=[O:10])[CH3:11])[cH:7]1.[K+:39].[K+:40].[O-:41][C:42]([O-:43])=[O:44].[O:45]=[CH:46][N:47]([CH3:48])[CH3:49]>>[F:1][c:2]1[c:3](-[c:12]2[n:13][cH:14][c:15]([O:18][CH2:24][CH:25]3[CH2:26][CH2:27][N:28]([c:31]4[n:32][c:33]([CH:36]([CH3:37])[CH3:38])[n:34][o:35]4)[CH2:29][CH2:30]3)[n:16][cH:17]2)[cH:4][cH:5][c:6]([S:8](=[O:9])(=[O:10])[CH3:11])[cH:7]1

Participants

6

Reactant 5

HCID 813Potassium Cation2×HCID 6228DimethylformamideHCID 19660Carbonate IonHCID 57930198(1-(3-Isopropyl-1,2,4-oxadiazol-5-yl)piperidin-4-yl)methyl methanesulfonateHCID 178504684HCID 178504684, compound

Product 1

HCID 249955892-[2-Fluoro-4-(methylsulfonyl)phenyl]-5-[({1-[3-(1-methylethyl)-1,2,4-oxadiazol-5-yl]-4-piperidinyl}methyl)oxy]pyrazine

Sources & evidence

ORD record
ord-fb1e2a903aa44dc2b0cfc7b462d263d0
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (7/10)

Reaction notes

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