Tetrahydrofuran → 1-[3-[[2-Methyl-5-nitro-6-(1,2,4,5-tetrahydro-3-benzazepin-3-yl)pyrimidin-4-yl]amino]propyl]pyrrolidin-2-one

HRID 1113986Notes

Reaction equation

HRID 1113986 reaction equation
[Cl:1][c:2]1[c:3]([N+:20](=[O:21])[O-:22])[c:4]([N:9]2[CH2:10][CH2:11][c:12]3[c:13]([cH:16][cH:17][cH:18][cH:19]3)[CH2:14][CH2:15]2)[n:5][c:6]([CH3:8])[n:7]1.[NH2:23][CH2:24][CH2:25][CH2:26][N:27]1[C:28](=[O:32])[CH2:29][CH2:30][CH2:31]1.[O:33]1[CH2:34][CH2:35][CH2:36][CH2:37]1>>[c:2]1([NH:23][CH2:24][CH2:25][CH2:26][N:27]2[C:28](=[O:32])[CH2:29][CH2:30][CH2:31]2)[c:3]([N+:20](=[O:21])[O-:22])[c:4]([N:9]2[CH2:10][CH2:11][c:12]3[c:13]([cH:16][cH:17][cH:18][cH:19]3)[CH2:14][CH2:15]2)[n:5][c:6]([CH3:8])[n:7]1

Participants

4

Reactant 3

HCID 8028TetrahydrofuranHCID 821111-(3-Aminopropyl)-2-pyrrolidinoneHCID 220039033-(6-Chloro-2-methyl-5-nitropyrimidin-4-yl)-1,2,4,5-tetrahydro-3-benzazepine

Product 1

HCID 699448491-[3-[[2-Methyl-5-nitro-6-(1,2,4,5-tetrahydro-3-benzazepin-3-yl)pyrimidin-4-yl]amino]propyl]pyrrolidin-2-one

Sources & evidence

ORD record
ord-c1ae79967d984d68a369a6c3b366ff95
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (7/10)

Reaction notes

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