Isopropanol → 1-[trans-4-(tert-butyl-dimethyl-silanyloxy)-cyclohexyl]-3-(4-methoxy-phenyl)-7-(4-methoxy-phenylamino)-3,4-dihydro-1H-pyrimido[4,5-d]pyrimidin-2-one
Reaction equation
[C:1]([CH3:2])([CH3:3])([CH3:4])[Si:5]([O:6][CH:7]1[CH2:8][CH2:9][CH:10]([N:13]2[C:14](=[O:32])[N:15]([c:24]3[cH:25][cH:26][c:27]([O:30][CH3:31])[cH:28][cH:29]3)[CH2:16][c:17]3[c:18]2[n:19][c:20]([Cl:23])[n:21][cH:22]3)[CH2:11][CH2:12]1)([CH3:33])[CH3:34].[CH3:35][O:36][c:37]1[cH:38][cH:39][c:40]([NH2:43])[cH:41][cH:42]1.[CH3:44][CH:45]([OH:46])[CH3:47]>>[C:1]([CH3:2])([CH3:3])([CH3:4])[Si:5]([O:6][CH:7]1[CH2:8][CH2:9][CH:10]([N:13]2[C:14](=[O:32])[N:15]([c:24]3[cH:25][cH:26][c:27]([O:30][CH3:31])[cH:28][cH:29]3)[CH2:16][c:17]3[c:18]2[n:19][c:20]([NH:43][c:40]2[cH:39][cH:38][c:37]([O:36][CH3:35])[cH:42][cH:41]2)[n:21][cH:22]3)[CH2:11][CH2:12]1)([CH3:33])[CH3:34]Participants
4
Sources & evidence
- ORD record
- ord-1ada6c084658409b9a8eb5d891fba800
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (7/10)
Reaction notes
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