Dichloromethane → [4-[2-(4-Benzyl-3-hydroxypiperidin-1-yl)ethylsulfonyl]phenyl] 4-(morpholin-4-ylmethyl)benzoate

HRID 1114474Notes

Reaction equation

HRID 1114474 reaction equation
[CH2:1]([c:2]1[cH:3][cH:4][cH:5][cH:6][cH:7]1)[CH:8]1[CH:9]([OH:36])[CH2:10][N:11]([CH2:14][CH2:15][S:16](=[O:17])(=[O:18])[c:19]2[cH:20][cH:21][c:22]([O:25][C:26]([c:27]3[cH:28][cH:29][c:30]([CH2:33][Cl:34])[cH:31][cH:32]3)=[O:35])[cH:23][cH:24]2)[CH2:12][CH2:13]1.[CH2:44]1[CH2:45][O:46][CH2:47][CH2:48][NH:49]1.[CH3:37][CH2:38][N:39]([CH2:40][CH3:41])[CH2:42][CH3:43].[Cl:50][CH2:51][Cl:52]>>[CH2:1]([c:2]1[cH:3][cH:4][cH:5][cH:6][cH:7]1)[CH:8]1[CH:9]([OH:36])[CH2:10][N:11]([CH2:14][CH2:15][S:16](=[O:17])(=[O:18])[c:19]2[cH:20][cH:21][c:22]([O:25][C:26]([c:27]3[cH:28][cH:29][c:30]([CH2:33][N:49]4[CH2:44][CH2:45][O:46][CH2:47][CH2:48]4)[cH:31][cH:32]3)=[O:35])[cH:23][cH:24]2)[CH2:12][CH2:13]1

Participants

5

Reactant 4

HCID 6344DichloromethaneHCID 8083MorpholineHCID 8471TriethylamineHCID 224502444-Chloromethyl-benzoic acid 4-[2-(4-benzyl-3-hydroxy-piperidin-1-yl)-ethanesulfonyl]-phenyl ester

Product 1

HCID 85338048[4-[2-(4-Benzyl-3-hydroxypiperidin-1-yl)ethylsulfonyl]phenyl] 4-(morpholin-4-ylmethyl)benzoate

Sources & evidence

ORD record
ord-68b3bf9e71fd42f49bfb88691227136f
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (7/10)

Reaction notes

Loading…