Tetrahydrofuran → 2-methyl-6-morpholino-1-(naphthalen-1-ylmethyl)-1H-benzo[d]imidazol-4-ol

HRID 1114636Notes

Reaction equation

HRID 1114636 reaction equation
[CH2:47]([N+:48]([CH2:49][CH2:50][CH2:51][CH3:52])([CH2:53][CH2:54][CH2:55][CH3:56])[CH2:57][CH2:58][CH2:59][CH3:60])[CH2:61][CH2:62][CH3:63].[CH2:64]1[O:65][CH2:66][CH2:67][CH2:68]1.[CH3:1][C:2]([Si:3]([c:4]1[cH:5][cH:34][cH:35][cH:36][cH:37]1)([O:6][c:7]1[cH:8][c:9]([N:28]2[CH2:29][CH2:30][O:31][CH2:32][CH2:33]2)[cH:10][c:11]2[n:12]([CH2:17][c:18]3[cH:19][cH:20][cH:21][c:22]4[cH:23][cH:24][cH:25][cH:26][c:27]34)[c:13]([CH3:16])[n:14][c:15]12)[c:38]1[cH:39][cH:40][cH:41][cH:42][cH:43]1)([CH3:44])[CH3:45].[F-:46]>>[OH:6][c:7]1[cH:8][c:9]([N:28]2[CH2:29][CH2:30][O:31][CH2:32][CH2:33]2)[cH:10][c:11]2[n:12]([CH2:17][c:18]3[cH:19][cH:20][cH:21][c:22]4[cH:23][cH:24][cH:25][cH:26][c:27]34)[c:13]([CH3:16])[n:14][c:15]12

Participants

5

Reactant 4

HCID 8028TetrahydrofuranHCID 16028TetrabutylammoniumHCID 28179Fluoride IonHCID 669769104-{[(1,1-dimethylethyl)(diphenyl)silyl]oxy}-2-methyl-6-(4-morpholinyl)-1-(1-naphthalenylmethyl)-1H-benzimidazole

Product 1

HCID 669762582-methyl-6-morpholino-1-(naphthalen-1-ylmethyl)-1H-benzo[d]imidazol-4-ol

Sources & evidence

ORD record
ord-6796fa993300475dbc38d3cfb50369f5
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (7/10)

Reaction notes

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