Dimethyl Sulfoxide → 2-(1-isopropyl-1H-1,2,4-triazol-5-yl)-5,6-dihydroimidazo[1,2-d]pyrido[3,4-f][1,4]oxazepine

HRID 1114670Notes

Reaction equation

HRID 1114670 reaction equation
[CH3:24][OH:25].[CH3:26][CH2:27][N:28]([CH2:29][CH3:30])[CH2:31][CH3:32].[CH3:34][S:35]([CH3:36])=[O:37].[Cl:1][c:2]1[cH:3][c:4]2[c:5]([cH:22][n:23]1)-[c:6]1[n:7]([cH:11][c:12](-[c:14]3[n:15][cH:16][n:17][n:18]3[CH:19]([CH3:20])[CH3:21])[n:13]1)[CH2:8][CH2:9][O:10]2.[Pd:33]>>[cH:2]1[cH:3][c:4]2[c:5]([cH:22][n:23]1)-[c:6]1[n:7]([cH:11][c:12](-[c:14]3[n:15][cH:16][n:17][n:18]3[CH:19]([CH3:20])[CH3:21])[n:13]1)[CH2:8][CH2:9][O:10]2

Participants

6

Reactant 5

HCID 679Dimethyl SulfoxideHCID 887MethanolHCID 8471TriethylamineHCID 23938PalladiumHCID 582045209-chloro-2-(1-isopropyl-1H-1,2,4-triazol-5-yl)-5,6-dihydroimidazo[1,2-d]pyrido[3,4-f][1,4]oxazepine

Product 1

HCID 582048782-(1-isopropyl-1H-1,2,4-triazol-5-yl)-5,6-dihydroimidazo[1,2-d]pyrido[3,4-f][1,4]oxazepine

Sources & evidence

ORD record
ord-e4438683c26646a6880e3a9f227afeb0
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (7/10)

Reaction notes

Loading…