Methanol → 1-(3,5-Difluorophenyl)-3-hydroxypyrrolidin-2-one
Reaction equation
[CH3:32][CH2:33][O:34][CH2:35][CH3:36].[CH3:37][OH:38].[F:1][c:2]1[cH:3][c:4]([NH:9][CH2:10][CH2:11][CH:12]2[C:13](=[O:19])[O:14][C:15]([CH3:17])([CH3:18])[O:16]2)[cH:5][c:6]([F:8])[cH:7]1.[OH2:20].[c:21]1([CH3:22])[cH:23][cH:24][c:25]([S:26]([OH:27])(=[O:28])=[O:29])[cH:30][cH:31]1>>[F:1][c:2]1[cH:3][c:4]([N:9]2[CH2:10][CH2:11][CH:12]([OH:16])[C:13]2=[O:14])[cH:5][c:6]([F:8])[cH:7]1Participants
6
Sources & evidence
- ORD record
- ord-7097fc2282c14c1ea50b911eaeb5df34
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (7/10)
Reaction notes
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