Dichloromethane → 2-(4-tert-Butyl-phenyl)-4-piperazin-1-yl-benzooxazole

HRID 1114770Notes

Reaction equation

HRID 1114770 reaction equation
[C:1]([O:2][C:3](=[O:4])[N:8]1[CH2:9][CH2:10][N:11]([c:14]2[cH:15][cH:16][cH:17][c:18]3[c:19]2[n:20][c:21](-[c:23]2[cH:24][cH:25][c:26]([C:29]([CH3:30])([CH3:31])[CH3:32])[cH:27][cH:28]2)[o:22]3)[CH2:12][CH2:13]1)([CH3:5])([CH3:6])[CH3:7].[CH2:40]([Cl:41])[Cl:42].[OH:33][C:34]([C:35]([F:36])([F:37])[F:38])=[O:39]>>[NH:8]1[CH2:9][CH2:10][N:11]([c:14]2[cH:15][cH:16][cH:17][c:18]3[c:19]2[n:20][c:21](-[c:23]2[cH:24][cH:25][c:26]([C:29]([CH3:30])([CH3:31])[CH3:32])[cH:27][cH:28]2)[o:22]3)[CH2:12][CH2:13]1

Participants

4

Reactant 3

HCID 6344DichloromethaneHCID 6422Trifluoroacetic acidHCID 576783004-[2-(4-tert-Butyl-phenyl)-benzooxazol-4-yl]-piperazine-1-carboxylic acid tert-butyl ester

Product 1

HCID 576783102-(4-tert-Butyl-phenyl)-4-piperazin-1-yl-benzooxazole

Sources & evidence

ORD record
ord-86ec8f9d553f427f803dbfca5c5fa8b7
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (7/10)

Reaction notes

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