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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1114798Generated: October 27, 2026

Water → 4-(5-Fluoro-2-methoxy-phenyl)-4-hydroxy-piperidine-1-carboxylic acid ethyl ester

https://huagongshe.com/reaction/1114798

Reaction equation

Participants

RoleNameHCIDCharge
ReactantWaterHCID 962—
ReactantTetrahydrofuranHCID 8028—
ReactantEthyl AcetateHCID 8857—
ReactantEthyl 4-oxo-1-piperidinecarboxylateHCID 34767—
Reactant2-Bromo-4-fluoroanisoleHCID 136292—
ReactantButyllithiumHCID 178418339—
Product4-(5-Fluoro-2-methoxy-phenyl)-4-hydroxy-piperidine-1-carboxylic acid ethyl esterHCID 68684824—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetTraining data from https://doi.org/10.1039/C8SC04228D (7/10)
ORD IDord-6d2185a192d243c08882930548d69b2f
Source noteTraining data from https://doi.org/10.1039/C8SC04228D (7/10)