Water → 4-(5-Fluoro-2-methoxy-phenyl)-4-hydroxy-piperidine-1-carboxylic acid ethyl ester
Reaction equation
[Br:1][c:2]1[c:3]([O:9][CH3:10])[cH:4][cH:5][c:6]([F:8])[cH:7]1.[CH2:16]([Li:17])[CH2:18][CH2:19][CH3:20].[CH2:21]([CH3:22])[O:23][C:24](=[O:25])[N:26]1[CH2:27][CH2:28][C:29](=[O:32])[CH2:30][CH2:31]1.[CH3:33][CH2:34][O:35][C:36](=[O:37])[CH3:38].[O:11]1[CH2:12][CH2:13][CH2:14][CH2:15]1.[OH2:39]>>[c:2]1([C:29]2([OH:32])[CH2:28][CH2:27][N:26]([C:24]([O:23][CH2:21][CH3:22])=[O:25])[CH2:31][CH2:30]2)[c:3]([O:9][CH3:10])[cH:4][cH:5][c:6]([F:8])[cH:7]1Participants
7
Sources & evidence
- ORD record
- ord-6d2185a192d243c08882930548d69b2f
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (7/10)
Reaction notes
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