Tetrahydrofuran → N-tert-butoxycarbonyl 1-(2-trimethylsilyl-5-fluorobenzofur-7-yl)-2-aminopropane
Reaction equation
[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6](=[O:7])[NH:8][CH:9]([CH2:10][c:11]1[cH:12][c:13]([F:20])[cH:14][c:15]2[cH:16][cH:17][o:18][c:19]12)[CH3:21].[CH2:22]([Li:23])[CH2:24][CH2:25][CH3:26].[CH3:27][Si:28]([CH3:29])([CH3:30])[N:31]=[C:32]=[O:33].[O:34]1[CH2:35][CH2:36][CH2:37][CH2:38]1>>[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6](=[O:7])[NH:8][CH:9]([CH2:10][c:11]1[cH:12][c:13]([F:20])[cH:14][c:15]2[cH:16][c:17]([Si:28]([CH3:27])([CH3:29])[CH3:30])[o:18][c:19]12)[CH3:21]Participants
5
Sources & evidence
- ORD record
- ord-9587ef3687134f82b7ef3a52bd51141c
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (7/10)
Reaction notes
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