Dichloromethane → 2-Amino-N-tert-butyl-5-chlorobenzamide

HRID 1114935Notes

Reaction equation

HRID 1114935 reaction equation
[C:35]([CH3:36])([CH3:37])([CH3:38])[NH2:39].[CH:20]1([N:21]=[C:22]=[N:23][CH:24]2[CH2:25][CH2:26][CH2:27][CH2:28][CH2:29]2)[CH2:30][CH2:31][CH2:32][CH2:33][CH2:34]1.[Cl:40][CH2:41][Cl:42].[NH2:1][c:2]1[c:3]([C:4](=[O:5])[OH:6])[cH:7][c:8]([Cl:11])[cH:9][cH:10]1.[OH:12][N:13]1[C:14](=[O:15])[CH2:16][CH2:17][C:18]1=[O:19]>>[NH2:1][c:2]1[c:3]([C:4](=[O:6])[NH:39][C:35]([CH3:36])([CH3:37])[CH3:38])[cH:7][c:8]([Cl:11])[cH:9][cH:10]1

Participants

6

Reactant 5

HCID 6344DichloromethaneHCID 6385Tert-ButylamineHCID 10868DicyclohexylcarbodiimideHCID 124762-Amino-5-chlorobenzoic acidHCID 80170N-Hydroxysuccinimide

Product 1

HCID 167703662-Amino-N-tert-butyl-5-chlorobenzamide

Sources & evidence

ORD record
ord-a6ede77da33e4b3a8176e924ffffb3dd
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (7/10)

Reaction notes

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