Toluene → 3-[2-(4-Cyanophenyl)-ethynyl]-2,5-dimethoxy-tetrahydrofuran
Reaction equation
[CH3:1][O:2][CH:3]1[O:4][CH:5]([O:23][CH3:24])[CH2:6][CH:7]1[C:8]#[C:9][Sn:10]([CH2:11][CH2:12][CH2:13][CH3:14])([CH2:15][CH2:16][CH2:17][CH3:18])[CH2:19][CH2:20][CH2:21][CH3:22].[CH3:34][c:35]1[cH:36][cH:37][cH:38][cH:39][cH:40]1.[I:25][c:26]1[cH:27][cH:28][c:29]([C:30]#[N:31])[cH:32][cH:33]1.[Pd:41].[c:42]1([P:43]([c:44]2[cH:45][cH:46][cH:47][cH:48][cH:49]2)[c:50]2[cH:51][cH:52][cH:53][cH:54][cH:55]2)[cH:56][cH:57][cH:58][cH:59][cH:60]1.[c:61]1([P:62]([c:63]2[cH:64][cH:65][cH:66][cH:67][cH:68]2)[c:69]2[cH:70][cH:71][cH:72][cH:73][cH:74]2)[cH:75][cH:76][cH:77][cH:78][cH:79]1.[c:80]1([P:81]([c:82]2[cH:83][cH:84][cH:85][cH:86][cH:87]2)[c:88]2[cH:89][cH:90][cH:91][cH:92][cH:93]2)[cH:94][cH:95][cH:96][cH:97][cH:98]1.[c:99]1([P:100]([c:101]2[cH:102][cH:103][cH:104][cH:105][cH:106]2)[c:107]2[cH:108][cH:109][cH:110][cH:111][cH:112]2)[cH:113][cH:114][cH:115][cH:116][cH:117]1>>[CH3:1][O:2][CH:3]1[O:4][CH:5]([O:23][CH3:24])[CH2:6][CH:7]1[C:8]#[C:9][c:26]1[cH:27][cH:28][c:29]([C:30]#[N:31])[cH:32][cH:33]1Participants
6
Sources & evidence
- ORD record
- ord-2724a9383aba4d3394206aafc2849233
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (7/10)
Reaction notes
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