Dimethylformamide → 4-amino-8-((5-chloro-3-(2-methoxyphenyl)-4-oxo-3,4-dihydroquinazolin-2-yl)methyl)pyrido[2,3-d]pyrimidin-5(8H)-one
Reaction equation
[C:13](=[O:14])([O-:15])[O-:16].[Cl:19][c:20]1[c:21]2[c:22](=[O:40])[n:23](-[c:32]3[c:33]([O:38][CH3:39])[cH:34][cH:35][cH:36][cH:37]3)[c:24]([CH2:30][Cl:31])[n:25][c:26]2[cH:27][cH:28][cH:29]1.[Cs+:17].[Cs+:18].[NH2:1][c:2]1[c:3]2[c:4]([n:5][cH:6][n:7]1)[nH:8][cH:9][cH:10][c:11]2=[O:12].[O:41]=[CH:42][N:43]([CH3:44])[CH3:45]>>[NH2:1][c:2]1[c:3]2[c:4]([n:5][cH:6][n:7]1)[n:8]([CH2:30][c:24]1[n:23](-[c:32]3[c:33]([O:38][CH3:39])[cH:34][cH:35][cH:36][cH:37]3)[c:22](=[O:40])[c:21]3[c:20]([Cl:19])[cH:29][cH:28][cH:27][c:26]3[n:25]1)[cH:9][cH:10][c:11]2=[O:12]Participants
6
Reactant 5
Product 1
Sources & evidence
- ORD record
- ord-334a328a88ec4bf9b4b2ceece8038255
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (7/10)
Reaction notes
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