Dichloromethane → Methyl 2-amino-5-(trifluoromethyl)benzoate

HRID 1115953Notes

Reaction equation

HRID 1115953 reaction equation
[C:1]([O:2][C:3](=[O:4])[NH:8][c:9]1[c:10]([C:11](=[O:12])[O:13][CH3:14])[cH:15][c:16]([C:19]([F:20])([F:21])[F:22])[cH:17][cH:18]1)([CH3:5])([CH3:6])[CH3:7].[CH2:23]([Cl:24])[Cl:25].[OH:26][C:27]([C:28]([F:29])([F:30])[F:31])=[O:32]>>[NH2:8][c:9]1[c:10]([C:11](=[O:12])[O:13][CH3:14])[cH:15][c:16]([C:19]([F:20])([F:21])[F:22])[cH:17][cH:18]1

Participants

4

Reactant 3

HCID 6344DichloromethaneHCID 6422Trifluoroacetic acidHCID 22672049Methyl 2-((tert-butoxycarbonyl)amino)-5-(trifluoromethyl)benzoate

Product 1

HCID 14233808Methyl 2-amino-5-(trifluoromethyl)benzoate

Sources & evidence

ORD record
ord-dbb9a04947bd4a66bc8ae9e3d7b131fc
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (7/10)

Reaction notes

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