Chloride → 5-[3-Fluoro-4-(methylsulfonyl)phenyl]-2-methyl-1-[4-(4-thiazolyl)phenyl]-1H-pyrrole
Reaction equation
[Br:1][c:2]1[cH:3][cH:4][c:5](-[n:8]2[c:9](-[c:14]3[cH:15][c:16]([F:24])[c:17]([S:20](=[O:21])(=[O:22])[CH3:23])[cH:18][cH:19]3)[cH:10][cH:11][c:12]2[CH3:13])[cH:6][cH:7]1.[CH2:25]([Sn:26]([CH2:27][CH2:28][CH2:29][CH3:35])([c:30]1[n:31][cH:32][s:33][cH:34]1)[CH2:36][CH2:37][CH2:38][CH3:39])[CH2:40][CH2:41][CH3:42].[CH2:44]1[O:45][CH2:46][CH2:47][O:48][CH2:49]1.[Cl-:43].[cH:50]1[cH:51][cH:52][c:53]([P:54]([Pd:55]([P:56]([c:57]2[cH:58][cH:59][cH:60][cH:61][cH:62]2)([c:63]2[cH:64][cH:65][cH:66][cH:67][cH:68]2)[c:69]2[cH:70][cH:71][cH:72][cH:73][cH:74]2)([P:75]([c:76]2[cH:77][cH:78][cH:79][cH:80][cH:81]2)([c:82]2[cH:83][cH:84][cH:85][cH:86][cH:87]2)[c:88]2[cH:89][cH:90][cH:91][cH:92][cH:93]2)[P:94]([c:95]2[cH:96][cH:97][cH:98][cH:99][cH:100]2)([c:101]2[cH:102][cH:103][cH:104][cH:105][cH:106]2)[c:107]2[cH:108][cH:109][cH:110][cH:111][cH:112]2)([c:113]2[cH:114][cH:115][cH:116][cH:117][cH:118]2)[c:119]2[cH:120][cH:121][cH:122][cH:123][cH:124]2)[cH:125][cH:126]1>>[c:2]1(-[c:30]2[n:31][cH:32][s:33][cH:34]2)[cH:3][cH:4][c:5](-[n:8]2[c:9](-[c:14]3[cH:15][c:16]([F:24])[c:17]([S:20](=[O:21])(=[O:22])[CH3:23])[cH:18][cH:19]3)[cH:10][cH:11][c:12]2[CH3:13])[cH:6][cH:7]1Participants
6
Reactant 5
Product 1
Sources & evidence
- ORD record
- ord-4abdad1b3938466dbac1159dbf0e7fec
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (7/10)
Reaction notes
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