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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1116158Generated: November 2, 2026

Bicarbonate Ion → (+)-6-fluoro-5-methoxy-1-[(1H-indazol-4-yl)amino]-4,4-dimethyl-2-(trifluoromethyl)-1,2,3,4-tetrahydronaphthalen-2-ol

https://huagongshe.com/reaction/1116158

Reaction equation

Participants

RoleNameHCIDCharge
ReactantBicarbonate IonHCID 769—
ReactantSodium ionHCID 923—
ReactantDichloromethaneHCID 6344—
ReactantEthyl AcetateHCID 8857—
Reactant1,1,1-Trifluoro-4-(3-fluoro-2-methoxyphenyl)-2-[(1H-indazol-4-yl)iminomethyl]-4-methylpentan-2-olHCID 17989253—
Product(+)-6-fluoro-5-methoxy-1-[(1H-indazol-4-yl)amino]-4,4-dimethyl-2-(trifluoromethyl)-1,2,3,4-tetrahydronaphthalen-2-olHCID 68679948—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetTraining data from https://doi.org/10.1039/C8SC04228D (7/10)
ORD IDord-f513c78f825043759828a542316fa7d5
Source noteTraining data from https://doi.org/10.1039/C8SC04228D (7/10)