Bicarbonate Ion → (+)-6-fluoro-5-methoxy-1-[(1H-indazol-4-yl)amino]-4,4-dimethyl-2-(trifluoromethyl)-1,2,3,4-tetrahydronaphthalen-2-ol
Reaction equation
[C:31](=[O:32])([OH:33])[O-:34].[CH3:36][CH2:37][O:38][C:39](=[O:40])[CH3:41].[Cl:42][CH2:43][Cl:44].[F:1][C:2]([C:3]([CH2:4][C:5]([CH3:6])([CH3:7])[c:8]1[c:9]([O:15][CH3:16])[c:10]([F:14])[cH:11][cH:12][cH:13]1)([OH:17])[CH:18]=[N:19][c:20]1[c:21]2[cH:22][n:23][nH:24][c:25]2[cH:26][cH:27][cH:28]1)([F:29])[F:30].[Na+:35]>>[F:1][C:2]([C:3]1([OH:17])[CH2:4][C:5]([CH3:6])([CH3:7])[c:8]2[c:9]([O:15][CH3:16])[c:10]([F:14])[cH:11][cH:12][c:13]2[CH:18]1[NH:19][c:20]1[c:21]2[cH:22][n:23][nH:24][c:25]2[cH:26][cH:27][cH:28]1)([F:29])[F:30]Participants
6
Reactant 5
Product 1
Sources & evidence
- ORD record
- ord-f513c78f825043759828a542316fa7d5
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (7/10)
Reaction notes
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