Dichloromethane → 2-(Bromomethyl)-4-fluorophenyl difluoro[4'-(trifluoromethyl)biphenyl-4-yl]methyl ether
Reaction equation
[Br:49][C:50]([Br:51])([Br:52])[Br:53].[Cl:54][CH2:55][Cl:56].[F:1][C:2]([O:3][c:4]1[c:5]([CH2:11][OH:12])[cH:6][c:7]([F:10])[cH:8][cH:9]1)([c:13]1[cH:14][cH:15][c:16](-[c:19]2[cH:20][cH:21][c:22]([C:25]([F:26])([F:27])[F:28])[cH:23][cH:24]2)[cH:17][cH:18]1)[F:29].[c:30]1([P:31]([c:32]2[cH:33][cH:34][cH:35][cH:36][cH:37]2)[c:38]2[cH:39][cH:40][cH:41][cH:42][cH:43]2)[cH:44][cH:45][cH:46][cH:47][cH:48]1>>[F:1][C:2]([O:3][c:4]1[c:5]([CH2:11][Br:49])[cH:6][c:7]([F:10])[cH:8][cH:9]1)([c:13]1[cH:14][cH:15][c:16](-[c:19]2[cH:20][cH:21][c:22]([C:25]([F:26])([F:27])[F:28])[cH:23][cH:24]2)[cH:17][cH:18]1)[F:29]Participants
5
Sources & evidence
- ORD record
- ord-3378e80bdbc84bb79ff402a31e1df478
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (7/10)
Reaction notes
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