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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1116269Generated: October 27, 2026

Hydrochloric Acid → 4-Difluoromethoxymethyl-pyrrolidine-1,2-dicarboxylic acid 2-[2-(4-bromo-phenyl)-2-oxo-ethyl]ester 1-tert-butyl ester

https://huagongshe.com/reaction/1116269

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHydrochloric AcidHCID 313—
ReactantMethanolHCID 887—
ReactantHydroxideHCID 961—
Reactant4-Bromophenacyl bromideHCID 7454—
ReactantTriethylamineHCID 8471—
ReactantLithium ionHCID 28486—
Reactant4-Difluoromethoxymethyl-pyrrolidine-1,2-dicarboxylic acid 1-tert-butyl ester 2-methyl esterHCID 66620438—
Product4-Difluoromethoxymethyl-pyrrolidine-1,2-dicarboxylic acid 2-[2-(4-bromo-phenyl)-2-oxo-ethyl]ester 1-tert-butyl esterHCID 66788989—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetTraining data from https://doi.org/10.1039/C8SC04228D (7/10)
ORD IDord-a0149e2004cf4ba4a57dd73d51a3bac1
Source noteTraining data from https://doi.org/10.1039/C8SC04228D (7/10)