HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1116341Generated: November 1, 2026
1,4-Dioxane → N-Cyclopropyl-6-[3-(4-fluoro-phenyl)-5-hydroxymethyl-isoxazol-4-ylmethoxy]-nicotinamide
https://huagongshe.com/reaction/1116341
Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | 1,4-Dioxane | HCID 31275 | — |
| Reactant | Cyclopropylamine | HCID 69828 | — |
| Reactant | Trimethylaluminum | HCID 16682925 | — |
| Reactant | 6-[3-(4-Fluoro-phenyl)-5-hydroxymethyl-isoxazol-4-ylmethoxy]-nicotinic acid methyl ester | HCID 66718131 | — |
| Product | N-Cyclopropyl-6-[3-(4-fluoro-phenyl)-5-hydroxymethyl-isoxazol-4-ylmethoxy]-nicotinamide | HCID 46928573 | — |
Provenance & Evidence
| DOI | 10.1039/C8SC04228D |
|---|
| Source dataset | Training data from https://doi.org/10.1039/C8SC04228D (7/10) |
|---|
| ORD ID | ord-346195b104794864b21ebf545d420b11 |
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| Source note | Training data from https://doi.org/10.1039/C8SC04228D (7/10) |
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