1,4-Dioxane → N-Cyclopropyl-6-[3-(4-fluoro-phenyl)-5-hydroxymethyl-isoxazol-4-ylmethoxy]-nicotinamide
Reaction equation
[CH3:1][Al:2]([CH3:3])[CH3:4].[CH3:9][O:10][C:11]([c:12]1[cH:13][n:14][c:15]([O:18][CH2:19][c:20]2[c:21](-[c:27]3[cH:28][cH:29][c:30]([F:33])[cH:31][cH:32]3)[n:22][o:23][c:24]2[CH2:25][OH:26])[cH:16][cH:17]1)=[O:34].[CH:5]1([NH2:8])[CH2:6][CH2:7]1.[O:35]1[CH2:36][CH2:37][O:38][CH2:39][CH2:40]1>>[CH:5]1([NH:8][C:11](=[O:10])[c:12]2[cH:13][n:14][c:15]([O:18][CH2:19][c:20]3[c:21](-[c:27]4[cH:28][cH:29][c:30]([F:33])[cH:31][cH:32]4)[n:22][o:23][c:24]3[CH2:25][OH:26])[cH:16][cH:17]2)[CH2:6][CH2:7]1Participants
5
Sources & evidence
- ORD record
- ord-346195b104794864b21ebf545d420b11
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (7/10)
Reaction notes
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