Dichloromethane → ethyl 5-amino-3-methylthiophene-2-carboxylate

HRID 1116371Notes

Reaction equation

HRID 1116371 reaction equation
[C:1]([O:2][C:3](=[O:4])[NH:8][c:9]1[cH:10][c:11]([CH3:19])[c:12]([C:14](=[O:15])[O:16][CH2:17][CH3:18])[s:13]1)([CH3:5])([CH3:6])[CH3:7].[Cl:27][CH2:28][Cl:29].[OH:20][C:21]([C:22]([F:23])([F:24])[F:25])=[O:26]>>[NH2:8][c:9]1[cH:10][c:11]([CH3:19])[c:12]([C:14](=[O:15])[O:16][CH2:17][CH3:18])[s:13]1

Participants

4

Reactant 3

HCID 6344DichloromethaneHCID 6422Trifluoroacetic acidHCID 43623126HCID 43623126, compound

Product 1

HCID 2064026ethyl 5-amino-3-methylthiophene-2-carboxylate

Sources & evidence

ORD record
ord-2af633391ba24234a4490c5346759cf0
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (7/10)

Reaction notes

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