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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 111643Generated: October 25, 2026

Tetrahydrofuran → 4-chloro-N-{[4-chloro-3-({3-chloro-5-[(trimethylsilyl)ethynyl]phenyl}oxy)-2-fluorophenyl]methyl}-1-({[2-(trimethylsilyl)ethyl]oxy}methyl)-1H-imidazole-5-carboxamide

https://huagongshe.com/reaction/111643

Reaction equation

Participants

RoleNameHCIDCharge
ReactantTetrahydrofuranHCID 8028—
ReactantTrimethylsilylacetyleneHCID 66111—
ReactantCopper iodideHCID 83717—
ReactantN-({3-[(3-bromo-5-chlorophenyl)oxy]-4-chloro-2-fluorophenyl}methyl)-4-chloro-1-({[2-(trimethylsilyl)ethyl]oxy}methyl)-1H-imidazole-5-carboxamideHCID 68487164—
Product4-chloro-N-{[4-chloro-3-({3-chloro-5-[(trimethylsilyl)ethynyl]phenyl}oxy)-2-fluorophenyl]methyl}-1-({[2-(trimethylsilyl)ethyl]oxy}methyl)-1H-imidazole-5-carboxamideHCID 68486613—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetTraining data from https://doi.org/10.1039/C8SC04228D (2/10)
ORD IDord-fd508c6dbbe549cd9e0f0033a52ee5bb
Source noteTraining data from https://doi.org/10.1039/C8SC04228D (2/10)