Toluene → 5-(3-Bromo-phenyl)-5-trifluoromethyl-morpholin-3-one

HRID 111699Notes

Reaction equation

HRID 111699 reaction equation
[CH2:1]([O:3][C:4](=[O:2])[CH2:5][O:6][CH2:7][C:8]([C:9]([F:10])([F:11])[F:12])([c:13]1[cH:14][c:15]([Br:19])[cH:16][cH:17][cH:18]1)[NH2:20])[CH3:21].[CH3:22][c:23]1[cH:24][cH:25][cH:26][cH:27][cH:28]1.[F:29][C:30]([F:31])([F:32])[C:33]([OH:34])=[O:35]>>[O:3]=[C:4]1[CH2:5][O:6][CH2:7][C:8]([C:9]([F:10])([F:11])[F:12])([c:13]2[cH:14][c:15]([Br:19])[cH:16][cH:17][cH:18]2)[NH:20]1

Participants

4

Reactant 3

HCID 1140TolueneHCID 6422Trifluoroacetic acidHCID 66666183[2-Amino-2-(3-bromo-phenyl)-3,3,3-trifluoro-propoxy]-acetic acid ethyl ester

Product 1

HCID 666654105-(3-Bromo-phenyl)-5-trifluoromethyl-morpholin-3-one

Sources & evidence

ORD record
ord-f982403f8f9545628fd77e7961a2fc98
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (2/10)

Reaction notes

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