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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1117012Generated: November 2, 2026

Tetrahydrofuran → N-{5-[(2-Chloro-4-pyrimidinyl)ethynyl]-2-methylphenyl}-2,2,2-trifluoroacetamide

https://huagongshe.com/reaction/1117012

Reaction equation

Participants

RoleNameHCIDCharge
ReactantTetrahydrofuranHCID 8028—
ReactantTriphenylphosphineHCID 11776—
ReactantPalladium ChlorideHCID 24290—
ReactantCopper(1+) iodide; Copper(I) iodide; Cuprous iodide; Cuprous iodide (CuI)HCID 24350—
Reactant2,4-DichloropyrimidineHCID 77531—
ReactantN-(5-Ethynyl-2-methylphenyl)-2,2,2-trifluoroacetamideHCID 57737207—
ProductN-{5-[(2-Chloro-4-pyrimidinyl)ethynyl]-2-methylphenyl}-2,2,2-trifluoroacetamideHCID 57737211—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetTraining data from https://doi.org/10.1039/C8SC04228D (7/10)
ORD IDord-6bf38d991f084cc1a80304a9e82423e1
Source noteTraining data from https://doi.org/10.1039/C8SC04228D (7/10)