Hydrochloric Acid → N-(5-Bromo-thiazol-2-yl)-3-cyclohexyl-2-(5,6-dichloro-1-oxo-1,3-dihydro-isoindol-2-yl)-propionamide

HRID 1117287Notes

Reaction equation

HRID 1117287 reaction equation
[CH:1]1([CH2:7][CH:8]([C:9](=[O:10])[OH:11])[N:12]2[C:13](=[O:23])[c:14]3[cH:15][c:16]([Cl:22])[c:17]([Cl:21])[cH:18][c:19]3[CH2:20]2)[CH2:2][CH2:3][CH2:4][CH2:5][CH2:6]1.[CH:32]1([CH2:33][CH:34]([N:35]2[CH2:36][c:37]3[c:38]([cH:39][cH:40][cH:41][cH:42]3)[C:43]2=[O:44])[C:45]([NH:46][c:47]2[s:48][cH:49][cH:50][n:51]2)=[O:52])[CH2:53][CH2:54][CH2:55][CH2:56][CH2:57]1.[ClH:24].[NH2:25][c:26]1[s:27][c:28]([Br:31])[cH:29][n:30]1>>[CH:1]1([CH2:7][CH:8]([C:9](=[O:10])[NH:25][c:26]2[s:27][c:28]([Br:31])[cH:29][n:30]2)[N:12]2[C:13](=[O:23])[c:14]3[cH:15][c:16]([Cl:22])[c:17]([Cl:21])[cH:18][c:19]3[CH2:20]2)[CH2:2][CH2:3][CH2:4][CH2:5][CH2:6]1

Participants

5

Reactant 4

HCID 313Hydrochloric AcidHCID 436002-Thiazolamine, 5-bromo-HCID 184021863-cyclohexyl-2-(5,6-dichloro-3-oxo-1H-isoindol-2-yl)propanoic acidHCID 184022003-cyclohexyl-2-(3-oxo-1H-isoindol-2-yl)-N-(1,3-thiazol-2-yl)propanamide

Product 1

HCID 18402213N-(5-Bromo-thiazol-2-yl)-3-cyclohexyl-2-(5,6-dichloro-1-oxo-1,3-dihydro-isoindol-2-yl)-propionamide

Sources & evidence

ORD record
ord-287eab25a4dd4a8ea4247b71c9de5af8
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (7/10)

Reaction notes

Loading…