Back
HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1117307Generated: October 26, 2026

Tetrahydrofuran → 3-[2-(2-Ethylbenzoimidazol-1-yl)-9-methyl-6-morpholin-4-yl-9H-purin-8-yl]-3-hydroxy-azetidine-1-carboxylic acid tert-butyl ester

https://huagongshe.com/reaction/1117307

Reaction equation

Participants

RoleNameHCIDCharge
ReactantTetrahydrofuranHCID 8028—
ReactantN,N,N',N'-TetramethylethylenediamineHCID 8037—
Reactant3-Oxo-azetidine-1-carboxylic acid tert-butyl esterHCID 1519404—
Reactant2-(2-Ethylbenzoimidazol-1-yl)-9-methyl-6-morpholin-4-yl-9H-purineHCID 59605494—
ReactantButyllithiumHCID 178418339—
Product3-[2-(2-Ethylbenzoimidazol-1-yl)-9-methyl-6-morpholin-4-yl-9H-purin-8-yl]-3-hydroxy-azetidine-1-carboxylic acid tert-butyl esterHCID 59605874—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetTraining data from https://doi.org/10.1039/C8SC04228D (7/10)
ORD IDord-57530a068fd045df8a01b3e885c1e386
Source noteTraining data from https://doi.org/10.1039/C8SC04228D (7/10)